Assistant Professor
Center for Fluorescence Spectroscopy
University of Maryland School of Medicine
Department of Biochemistry & Molecular Biology
725, West Lombard Street, Room: N270
Baltimore, MD 21201
Tel: 410-706-7500, Fax: 410-706-8408,
Contact by e-mail
Postdoctoral Associate, Yale University
Visiting Scientist, Weizmann Institute of Science
Ph.D., Spectroscopy, Jadavpur University, India
Thesis: Spectroscopic Investigation of Organic Molecules Organized in Langmuir-Blodgett Films
(Research work carried out at the Indian Association for the Cultivation of Science)
MS, Physics, Indian Institute of Technology, Kharagpur, India
BS, Major in Physics with Chemistry and Mathematics, University of Calcutta, India
Current Research Interests:
Single molecule imaging spectroscopy, Fluorescence correlation spectroscopy, Metal enhance fluorescence, Surface plasmon coupled emission, Plasmon-controlled fluorescence, Radiative decay engineering, Fluorescence spectroscopy, Chemically amplified photoresists, Langmuir-Blodgett films, Layer-by-layer assembly, Nanotechnology, Application of single molecule spectroscopy in biomedical research
Awards/Recognition:
• JSPS Fellowship
• ISCA Young Scientists’ Award, Indian Science Congress Association
Selected Publications:
35 papers in international peer-reviewed journals, 18 papers in international conference proceedings, 15 presentations
• K. Ray, S. Ananthavel, D. Waldeck, R. Naaman, Asymmetric Scattering of Polarized Electrons by Organized Organic Films of Chiral Molecules, Science, 283, 814 (1999)
• Krishanu Ray, H. Nakahara, Adsorption of Sulforhodamine in Cationic Langmuir-Blodgett Films: Spectroscopic and Structural Studies, Journal of Physical Chemistry B, 106, 92 (2002)
• M. Mason, Krishanu Ray, R. Grober, G. Pohlers, J. Cameron, Single Molecule Acid/base Kinetics and Thermodynamics, Physical Review Letters, 93, 073004 (2004)
• Krishanu Ray, M. Mason, G. Pohlers, J. Cameron, R. Grober, Quantum Yields of Photoacid Generation in 193nm Chemically Amplified Resists by Fluorescence Imaging Spectroscopy, Chemistry of Materials, 16, 5726 (2004)
• Krishanu Ray, M. Mason, C. Yang, Z. Li, R. Grober, Single Molecule Signal Enhancement using a HighIimpedance Ground Plane, Applied Physics Letters, 85, 5520 (2004)
• Krishanu Ray, R. Badugu, J. R. Lakowicz, Distance-Dependent Metal-Enhanced Fluorescence from Langmuir -Blodgett Monolayers of Alkyl-NBD Derivatives on Silver Island Films, Langmuir, 22, 8374-8378 (2006).
• Krishanu Ray, R. Badugu, J. R. Lakowicz, Langmuir-Blodgett Monolayers of Long-chain NBD Derivatives on Silver Island Films: Well Organized Probe Layer for the Metal Enhanced Fluorescence Studies, J. Phys. Chem. B , 110, 13499-13507 (2006).
• Krishanu Ray, R. Badugu, J. R. Lakowicz, Metal-Enhanced Fluorescence from CdTe Nanocrystals: A Single-Molecule Fluorescence Study, Journal of the American Chemical Society, 128, 8998-8999 (2006).
• Krishanu Ray, R. Badugu, J. R. Lakowicz, Sulforhodamine Adsorbed Langmuir-Blodgett Layers on Silver Island Films: Effect of Probe Distance on the Metal Enhanced Fluorescence, J. Phys. Chem. C 111, 7091-7097 (2007).
• Krishanu Ray, H. Szmacinski, J. Enderlein, J. R. Lakowicz, Distance-dependence of Surface Plasmon-Coupled Emission Observed Using Langmuir-Blodgett Films, Applied Physics Letters, 90, 251116 (2007).
• Krishanu Ray, M. Chowdhury, J. R. Lakowicz, Aluminum Nano-structured Films as Substrates for Enhanced Fluorescence in the Ultraviolet - Blue Spectral Region, Analytical Chemistry, Accelerated Article (2007).
Manuscript Reviewer: Reviewed a numbers of manuscripts for International Scientific Journals : Journal of Physical Chemistry, Clinical Chemistry, Journal of Photochemistry Photobiology A, Spectrochimica Acta A, Optical Materials, Thin Solid Films, Journal of Fluorescence, Journal of Vacuum Science and Tech. B, Macromolecules, Journal of Materials Chemistry, Journal of Biomedical Optics, Sensors and Actuators, Photochemistry and Photobiology.
Guest Editor: Special issue of ‘Journal of Fluorescence’ entitled “Advances in Single Molecule Spectroscopy”, November 2007.
Grant Reviewer: Netherlands Organisation for Scientific Research (NWO, the Dutch research council).
Past Research Experience:
Postdoctoral Associate, Yale University
• Spectroscopic imaging of acids in chemically amplified photoresists
• High-spatial resolution optical microscopy and imaging spectroscopy as a tool for materials characterization and metrology
• Single fluorescent molecules as nanoscale optical probes for the characterization of semiconductor materials and thin film polymers
• Developed a method for temperature dependent single-molecule fluorescence measurements to obtain proton exchange kinetics and thermodynamics
• Signal enhancement by high impedance ground plane substrates for single molecule imaging
• Advanced a non-destructive insitu technique for quantifying acid generation in industry relevant photoresist film systems
• Involved in investigating a multicolor polarization-sensitive fluorescence correlation technique for studying the mechanism and dynamics of amyloid fiber formation
• Involved in building a laser scanning confocal microscope
Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellow
• Spectroscopic and structural studies of functionalized Langmuir-Blodgett Films. Electron, energy and proton transfer in organized assembly
Postdoctoral Associate, University of Connecticut
• Preparation of self-assembled films by metal-organic chelation technique and its’ characterization
Visiting Scientist, Weizmann Institute of Science, Israel
• Electron transmission through organized organic thin films
Research Fellow, Indian Association for the Cultivation of Science
• Spectroscopic, structural and surface properties of Langmuir-Blodgett (LB) films. Fabrication of LB films. Monolayers at the air-water interface. Functionalization of LB films to investigate its application as sensors or devices. Time-resolved fluorescence spectroscopy, excitation energy transfer in organized assembly.